Solved.
The apply filter to route does not work unless you replot the route manually and I had messed up star classes. If I come across a related bug I will repost or resurrect this one.
Odyssey issue. Has anyone else found that you can no longer filter routes for star class from the Galaxy Map? I have repeatedly tried but the Apply to Filter button does nothing. It does not refresh the path and will not "recalculate route" as an option. Worse, when I manually cancel the route and reroute with the star classes filtered, the galaxy map will give me a new route. But the new route still includes stars from the omitted classes. It is as though the Apply to Filter function has been stealth removed from the game.
If you also have this issue, I put my issue tracker post below.
Source: https://www.reddit.com/r/EliteDangerous/comments/rip8yh/star_class_apply_to_filter_not_working/