On macros and disabilities

Hello guys,

TLDR: are macros allowed if they help a disabled person playing the game to a similar degree an able-bodied person would?

I've dragged a friend of mine into Dota after almost a decade of LoL. He's lost the use of his left arm and hand a while back, so his whole gaming experience has always revolved around macros. We are trying to set up his devices, he's using a Razer Naga mouse to which we're binding abilities and items, and a keypad next to the mouse to which we're binding keys that are used less but still quite important (shop, courier, fortify…).

We've got a couple of unbound keys and I was thinking to bind some key combination for stuff he definitely cannot do (some "shift+key" commands), and creating little macros to relieve a bit of stress onto his right hand and perform multiple actions with one button (dragging items in the backpack or on the ground to refill heal/mana and dragging it back to inventory).

I'm almost a decade into Dota myself and I've never had to think about the game in this way. Would a macro like that cause him some problems if caught?

Taking the thing to an extreme, since he plays mid and might as well try the hero one day: could he map invoker's skills so that a key triggers the whole combination of keys (eg. Q + W + E + R) to mimic an able-bodied player who would do that almost instantly using 3/4 fingers at once, instead of dragging his thumb across the mouse side keys, or would that really be too much?