Subj. I tend to prefer volume of fire over precision, and noticed my Factory performance improved significantly when loading in with two primaries.
E.g. when I had a quest to kill 8 scavs with a PPsh, I just loaded in with two of those and 3 drum mags (plus a couple sticks for good measure). I could spray a drum downrange, then if the enemy wasn't dead I just switched to the other SMG and rushed him while he reloaded (really a missed opportunity to play Billy Mays "But Wait There's More" over VOIP, too lazy for this).
When not using a specific gun for quest, I generally use a kektor/UMP as my primary and a scav 153 as my secondary. Those 8 rounds of magnum fuck are a godsend if kektor burst doesn't land right, and selling the gun to Mechanic is barely 10k rubbles (plus I'll get it back in insurance if I die).
Next plan: run factory with two double-barrels.
Source: https://www.reddit.com/r/EscapefromTarkov/comments/s9ifg1/anyone_else_use_2_guns_on_factory/